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Healthcare & Life Science Companies in South Dakota

9,708 companies in Healthcare & Life Science in South Dakota.

Explore 9,708 Healthcare & Life Science in South Dakota listed with contact details, employee size, revenue, and NAICS/SIC codes. Compare suppliers and service providers side by side and reach the right companies directly, or view the same industry in Healthcare & Life Science in California, Healthcare & Life Science in Florida, Healthcare & Life Science in Texas.

9,708Companies
10500+ employees
3$1B+ revenue
100%Revenue on file
Jul 17, 2026Last updated

Largest Healthcare & Life Science in South Dakota companies by revenue

The highest-revenue companies in this directory. Open any profile for its full firmographics.

#CompanyLocationEmployeesRevenue
1Sanford HealthSioux Falls55,000$8.1B
2Avera FoundationSioux Falls20,500$3B
3Monument HealthRapid City7,352$1.1B
4The Evangelical Lutheran Good Samaritan SocietySioux Falls15,000$800M
5AveraSioux Falls22,100$285M
6Avera McKennan Hospital & University CenterSioux Falls581$163M
7Avera HealthYankton1,353$143M
8Edith Sanford Breast Cancer FoundationSioux Falls83$95M
9McKennan HospitalGarretson283$94M
10Rapid City Medical Center LLPRapid City487$88M
Loren HoferHitchcock, South Dakota, United States · Healthcare & Life ScienceJennifer Greco, MDSioux Falls, South Dakota, United States · Healthcare & Life ScienceMabee Eye ClinicMitchell, South Dakota, United States · Healthcare & Life ScienceNikki R RabeBig Stone City, South Dakota, United States · Healthcare & Life ScienceThomas G Swanson DDSMobridge, South Dakota, United States · Healthcare & Life ScienceDr Sophia Chun, MDVermillion, South Dakota, United States · Healthcare & Life ScienceDr Paul Andrew TravnicekSioux Falls, South Dakota, United States · Healthcare & Life ScienceF Naessig, DDS, Prof.LLCSioux Falls, South Dakota, United States · Healthcare & Life ScienceBethann Kay McfarlandSpearfish, South Dakota, United States · Healthcare & Life SciencemcmahonMichael DHuron, South Dakota, United States · Healthcare & Life ScienceBrennan Allergy Clinic Prof LLCMiller, South Dakota, United States · Healthcare & Life ScienceDevon Wentz DCSpearfish, South Dakota, United States · Healthcare & Life ScienceJohnson Jana, MDSioux Falls, South Dakota, United States · Healthcare & Life ScienceSd Cameron Deschamp Od PCSioux Falls, South Dakota, United States · Healthcare & Life ScienceNewcastle Regional MedicalRapid City, South Dakota, United States · Healthcare & Life ScienceMegard, Daniel L, MDVermillion, South Dakota, United States · Healthcare & Life ScienceSanford ClinicHartford, South Dakota, United States · Healthcare & Life ScienceDakota Family Chiropractic Of Mitchell PCMitchell, South Dakota, United States · Healthcare & Life ScienceDr Jorge Ramiro ReynoRapid City, South Dakota, United States · Healthcare & Life ScienceShelly SmitLennox, South Dakota, United States · Healthcare & Life SciencePELDO JulieSpearfish, South Dakota, United States · Healthcare & Life ScienceNewkirk Bradall GPPierre, South Dakota, United States · Healthcare & Life ScienceChristine PawlowskiMiller, South Dakota, United States · Healthcare & Life ScienceDorothy DraskovicMc Intosh, South Dakota, United States · Healthcare & Life Science
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Healthcare & Life Science in South Dakota companies by size and revenue

By number of employees
EmployeesCompaniesShare
1-509,54498.3%
51-2001211.2%
201-1000360.4%
1001-500010.0%
5001+50.1%
By annual revenue
RevenueCompaniesShare
Under $10M9,60999.0%
$10M-$50M770.8%
$50M-$250M150.2%
$250M-$1B20.0%
$1B+30.0%

Share is of companies with a known value — 9,707 with headcount and 9,706 with revenue on file, as of Jul 17, 2026.

Frequently asked questions

How many Healthcare & Life Science in South Dakota are there?

There are 9,708 Healthcare & Life Science in South Dakota in the directory. Use the filters to narrow by employee count, revenue, or NAICS/SIC code.

How many large companies are in Healthcare & Life Science in South Dakota?

10 of the 9,708 companies in Healthcare & Life Science in South Dakota employ more than 500 people, and 3 report over $1 billion in annual revenue. See the size and revenue breakdown above for the full distribution.

What size are most Healthcare & Life Science in South Dakota companies?

Most are small and mid-sized businesses: the size and revenue tables above show the full spread, from under $10M up to $1B+, across the 9,706 companies with revenue on file.

What information is included for each company?

Every listing includes the company name, location, website, employee size, revenue range where available, and NAICS/SIC classification, with a link to the full profile.

Where does this directory come from?

Listings are compiled and maintained by Factur, a sales and marketing firm for B2B manufacturers. Any company can request an update or removal from its profile page.