317-622-8970Search all companies →Largest Healthcare & Life Science Companies in North Carolina (2026)
Factur's directory lists 114,780 healthcare & life science companies in North Carolina. These are the 10 largest of them by annual revenue, led by Advocate Health ($28B), Labcorp Holdings Inc ($14B) and Atrium Health ($10.3B).
Size mix: of the 114,780 with a known headcount, 98.6% have 1-50 employees, 1.1% 51-200, 271 companies 201-1000, 44 companies 1001-5000 and 22 companies 5001+. 125 employ more than 500 people.
The 10 largest healthcare & life science companies in North Carolina by annual revenue
| # | Company | City | Employees | Annual revenue |
|---|---|---|---|---|
| 1 | Advocate Health | Charlotte | 155,000 | $28B |
| 2 | Labcorp Holdings Inc | Burlington | 70,000 | $14B |
| 3 | Atrium Health | Charlotte | 70,000 | $10.3B |
| 4 | Novant Health | Winston Salem | 40,000 | $9.2B |
| 5 | UNC Health | Chapel Hill | 40,000 | $5.9B |
| 6 | Atrium Health Wake Forest Baptist Medical Center | Winston Salem | 14,000 | $5B |
| 7 | Duke University Health System | Raleigh | 26,278 | $3.9B |
| 8 | Carolinas HealthCare System | Charlotte | 58,901 | $3.4B |
| 9 | Six Flags Entertainment Corp | Charlotte | 5,000 | $3.1B |
| 10 | Lexington Memorial Hospital Inc | Lexington | 14,000 | $2.8B |
How this list is ranked
Companies are ranked by annual revenue (USD) as recorded on each company's profile in the Factur directory, highest first; companies with the same revenue are ordered by employee count. Only companies with a positive revenue figure on file are ranked, so a large private company with no reported revenue can be missing. The list covers companies whose record places them in North Carolina and whose Factur industry is Healthcare & Life Science. Figures are a snapshot of the directory, refreshed when the rankings are regenerated; open a profile for its current data.