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Largest Healthcare & Life Science Companies in Kentucky (2026)

Factur's directory lists 50,499 healthcare & life science companies in Kentucky. These are the 10 largest of them by annual revenue, led by KFC Corp ($30B), BrightSpring Health Services Inc ($12.9B) and Yum! Brands Inc ($8.2B).

Size mix: of the 50,499 with a known headcount, 98.8% have 1-50 employees, 424 companies 51-200, 150 companies 201-1000, 31 companies 1001-5000 and 18 companies 5001+. 80 employ more than 500 people.

The 10 largest healthcare & life science companies in Kentucky by annual revenue

#CompanyCityEmployeesAnnual revenue
1KFC CorpLouisville800,000$30B
2BrightSpring Health Services IncLouisville23,500$12.9B
3Yum! Brands IncLouisville40,000$8.2B
4Texas Roadhouse Delaware LLCLouisville101,000$5.9B
5Baptist HealthLouisville23,000$4B
6Norton HealthcareLouisville20,000$3.6B
7knight health holdings LLCLouisville47,562$3.2B
8Churchill Downs IncLouisville6,600$2.9B
9UofL HealthLouisville14,000$2.1B
10Atria Senior Living IncLouisville13,191$1.9B

How this list is ranked

Companies are ranked by annual revenue (USD) as recorded on each company's profile in the Factur directory, highest first; companies with the same revenue are ordered by employee count. Only companies with a positive revenue figure on file are ranked, so a large private company with no reported revenue can be missing. The list covers companies whose record places them in Kentucky and whose Factur industry is Healthcare & Life Science. Figures are a snapshot of the directory, refreshed when the rankings are regenerated; open a profile for its current data.