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Largest Healthcare & Life Science Companies in Nebraska (2026)

Factur's directory lists 24,396 healthcare & life science companies in Nebraska. These are the 10 largest of them by annual revenue, led by Home Instead Inc ($9.5B), Catholic Health Initiatives ($1.8B) and Nebraska Medical Center ($1.3B).

Size mix: of the 24,396 with a known headcount, 98.4% have 1-50 employees, 1.2% 51-200, 79 companies 201-1000, 11 companies 1001-5000 and 6 companies 5001+. 30 employ more than 500 people.

The 10 largest healthcare & life science companies in Nebraska by annual revenue

#CompanyCityEmployeesAnnual revenue
1Home Instead IncOmaha65,000$9.5B
2Catholic Health InitiativesOmaha12,588$1.8B
3Nebraska Medical CenterOmaha9,000$1.3B
4Nebraska Methodist Health SystemOmaha8,000$1.2B
5Corporate Travel Management (ctm) UsOmaha5,000$1B
6Nhs University HospitalOmaha2,017$888M
7Pine Lake Medical PlazaLincoln6,000$881M
8Bryan HealthLincoln5,704$837M
9Children's NebraskaOmaha4,177$647M
10Mary Lanning Memorial HospitalHastings747$317M

How this list is ranked

Companies are ranked by annual revenue (USD) as recorded on each company's profile in the Factur directory, highest first; companies with the same revenue are ordered by employee count. Only companies with a positive revenue figure on file are ranked, so a large private company with no reported revenue can be missing. The list covers companies whose record places them in Nebraska and whose Factur industry is Healthcare & Life Science. Figures are a snapshot of the directory, refreshed when the rankings are regenerated; open a profile for its current data.